- protein tyrosine kinase inhibitor
- ингибитор белковой тирозинкиназывещество, ингибирующее действие тирозинкиназы
English-Russian Biotechnology Glossary. A. F. Valikhov, V. V. Kolotvin, O. A. Legonkova, I. A. Rogov, Thomas Creamer. 2007.
English-Russian Biotechnology Glossary. A. F. Valikhov, V. V. Kolotvin, O. A. Legonkova, I. A. Rogov, Thomas Creamer. 2007.
tyrosine kinase inhibitor — any of a class of antineoplastic agents that inhibit protein tyrosine kinase and interfere with the action of epidermal growth factor in cancer cells … Medical dictionary
Bcr-Abl tyrosine-kinase inhibitor — Bcr Abl tyrosine kinase inhibitors (TKI) are the first line therapy for most patients with chronic myelogenous leukemia (CML). In more than 90% cases CML is caused by chromosomal abnormality resulting in the formation of a so called Philadelphia… … Wikipedia
Protein tyrosine phosphatase — Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Protein tyrosine (pTyr) phosphorylation is a common post translational modification that can create novel… … Wikipedia
Protein kinase inhibitor — A protein kinase inhibitor is a type of enzyme inhibitor which specifically blocks the action of protein kinase.Kinase inhibitors such as dasatinib are often used in the treatment of cancer and inflammation. Some of the kinase inhibitors used in… … Wikipedia
Non-receptor tyrosine kinase — non membrane spanning protein tyrosine kinase Identifiers EC number 2.7.10.2 Databases IntEnz In … Wikipedia
Cyclin-dependent kinase inhibitor 1C — (p57, Kip2) Identifiers Symbols CDKN1C; BWCR; BWS; KIP2; WBS; p57 External IDs … Wikipedia
Protein kinase A — In cell biology, Protein kinase A (PKA) refers to a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP dependent protein kinase (EC 2.7.11.11). Protein kinase A has several functions… … Wikipedia
Tyrosine hydroxylase — or tyrosine 3 monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L tyrosine to dihydroxyphenylalanine (DOPA). DOPA is a precursor for dopamine which in turn is a precursor for norepinephrine (noradrenaline)… … Wikipedia
Protein kinase — A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). This class of protein may further be separated into subsets as in the case of protein kinase C PKC alpha, PKC beta,… … Wikipedia
Dual-specificity kinase — Identifiers EC number 2.7.12.1 CAS number 134549 83 0 … Wikipedia
Secreted frizzled-related protein 1 — The Secreted frizzled related protein (SFRP) family consists of five secreted glycoproteins in humans ( 300 amino acids in length) that act as extracellular signaling ligands. Each SFRP contains a cysteine rich domain (CRD) that shares 30 50%… … Wikipedia